The advent of long-acting basal insulin weekly formulations represents a landmark milestone. While ensuring hypoglycemic efficacy and safety, it significantly reduces the injection burden, providing more treatment options for patients with type 2 diabetes (T2DM).At present, icodec insulin, the world’s first insulin weekly formulation, has been included in China’s medical insurance catalogue, and an increasing […]
Tag: Type 2 diabetes
Medications for Type 2 Diabetes with Obesity
For patients with type 2 diabetes mellitus (T2DM) and obesity, pharmacotherapy should achieve both glycemic control and weight reduction. Based on extensive research and multiple medical guidelines, the following is a recommended medication strategy for such patients.I. Cornerstone Drug: Metformin (First-Line)As a first-line agent, metformin acts through unique mechanisms: It achieves dual benefits: glucose lowering […]
Lipid Control Targets for Patients with Type 2 Diabetes
Diabetic dyslipidemia not only increases the risk of cardiovascular disease but also impairs islet function.Normal cholesterol levels are a prerequisite for maintaining proper function of pancreatic β-cells, whereas elevated cholesterol levels can induce apoptosis of pancreatic β-cells.Lipid control targets for patients with type 2 diabetes Note: Atherosclerotic cardiovascular disease includes coronary heart disease, cerebrovascular disease, […]
Two-step strategy predicts advanced liver fibrosis and long-term outcomes in patients with diabetes-fatty liver comorbidity
On January 21, Gut, an authoritative international journal of gastroenterology, online published a study entitled Two-step strategy for predicting advanced liver fibrosis and long-term outcomes in individuals with type 2 diabetes and metabolic dysfunction-associated fatty liver disease. This study provides an effective new approach for risk stratification in patients with type 2 diabetes mellitus (T2DM) […]
Moderate Strength Training Helps Women Prevent Type 2 Diabetes
A study has warned that moderate strength training in women can help prevent type 2 diabetes.Researchers from the Harvard T.H. Chan School of Public Health and the University of Southern Denmark followed 99,300 middle‑aged and older women for 8 years and conducted a detailed analysis of their lifestyle and exercise habits.The results showed that exercises […]
MASLD Increases All-Cause Mortality Risk in Type 2 Diabetes
Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly becoming one of the most prevalent chronic liver diseases worldwide. Although the disease directly impairs liver function, causing abnormal fat accumulation and hepatocellular injury, its most life-threatening threat often does not originate from liver lesions themselves. In fact, MASLD more commonly significantly elevates patients’ all-cause mortality risk […]
Three Types of People at High Risk of Type 2 Diabetes
Most patients with type 2 diabetes do not rely on insulin at the initial onset, and can use oral hypoglycemic drugs to control blood glucose. It is also known as non-insulin-dependent diabetes.The so-called “type 2 diabetes” develops through a long pathological process under the action of various pathogenic factors.Who are at high risk of type […]
Does the “2+N Systematic Therapy” Make Type 2 Diabetes Remission Possible?
For many people, a diagnosis of type 2 diabetes mellitus (T2DM) means lifelong medication, strict glucose control, and constant risk of complications. In recent years, however, the concept of diabetes remission has quietly changed clinical practice: it is not a cure, but scientific intervention that maintains blood glucose at a non-diabetic level long-term without medication, […]
Professor Ye Jianping: Type 2 Diabetes Roots in Excess Energy
At a public conference, Professor Ye Jianping from the Metabolic Disease Research Center of Zhengzhou University shared a series of studies and conclusions on the mechanistic exploration of type 2 diabetes mellitus (T2DM). He delivered an insightful explanation of the biological mechanisms underlying T2DM pathogenesis and summarized its clinical therapeutic strategies and the mechanisms of […]
What core indicators can accurately evaluate blood glucose stability in clinical practice?
Stable blood glucose control is crucial for the health management of patients with type 2 diabetes mellitus (T2DM), as reflected in the following three aspects:Daily healthStable blood glucose avoids discomfort caused by drastic fluctuations, such as dizziness, fatigue, and poor concentration. It helps patients maintain more energy for daily activities and achieve better appetite and […]