On January 15, 2026, the research team led by Professor Weng Jianping (President of Anhui Medical University, Chair Professor at University of Science and Technology of China) and Researcher Zheng Xueying published a study in Metabolism entitled “Integrative Functional Genomics and Fine-Mapping Identify Regulatory Mechanisms of Multivariate Obesity GWAS and Its Cardiometabolic Implications”.By constructing an […]
Tag: Obesity
Medications for Type 2 Diabetes with Obesity
For patients with type 2 diabetes mellitus (T2DM) and obesity, pharmacotherapy should achieve both glycemic control and weight reduction. Based on extensive research and multiple medical guidelines, the following is a recommended medication strategy for such patients.I. Cornerstone Drug: Metformin (First-Line)As a first-line agent, metformin acts through unique mechanisms: It achieves dual benefits: glucose lowering […]
Obesity Criteria and Assessment Items
Professor Li Xia from the Department of Metabolism and Endocrinology, the Second Xiangya Hospital of Central South University, points out that the iCARDIO Alliance Global Implementation Guidelines for Obesity Management 2025 defines overweight as a BMI of 23–27.5 kg/m² and obesity as a BMI ≥ 27.5 kg/m² for Chinese (Asian) populations. These thresholds are lower […]
Common Patterns and Precautions of Intermittent Fasting
Intermittent Fasting (IF) is an eating pattern that regulates metabolism by periodically restricting the eating window. Its core is to prolong the fasting period to achieve potential benefits such as weight loss and improved metabolic health. Common patterns include the 16:8 method (16 hours of fasting per day) and the 5:2 diet (2 days of […]
iCARDIO 2025 Guidelines Landmark Release: Redefining Obesity and Its Significance
Obesity has long been mistakenly regarded as merely a “physical appearance issue” or a “lifestyle choice.” In October 2025, the iCARDIO Alliance Global Implementation Guidelines for Obesity Management 2025 (iCARDIO 2025 Guidelines for short) was officially released. It clearly defines obesity as a chronic, relapsing, multifactorial metabolic disease and places it at the core of […]
Intervention and Treatment of Postmenopausal Sarcopenic Obesity
Exercise Intervention: Multiple guidelines recommend resistance training as the core strategy for treating SO. Studies in postmenopausal women confirm that regular resistance training can significantly improve muscle strength and body composition, including increasing lean body mass and reducing fat percentage, in a safe and feasible manner.Nutritional Intervention: According to the ESPEN (European Society for Clinical […]
Diagnosis of Postmenopausal Sarcopenic Obesity
At the 27th Annual Conference of the Chinese Society of Diabetes (CDS 2025), Professor Shen Jie from the Eighth Affiliated Hospital of Southern Medical University systematically elaborated on diagnostic approaches for postmenopausal sarcopenic obesity in this specific population.The European Working Group on Sarcopenia in Older People (EWGSOP2) clearly states that low muscle strength is the […]
Pathogenesis of Postmenopausal Sarcopenic Obesity
During the 27th Annual Conference of the Chinese Society of Diabetes (CDS 2025), a premier event in the diabetes field, top experts and scholars from across the country gathered to conduct in-depth exchanges on cutting-edge topics in endocrinology and metabolism, yielding fruitful academic outcomes. At the conference, Professor Shen Jie from the Eighth Affiliated Hospital […]
The Core of Precision Obesity Treatment is Patient-Centered Individualized Diagnosis and Therapy
Professor Hong Tianpei of Peking University Third Hospital holds that, with the continuous emergence of novel weight-loss medications — such as more potent GLP‑1 agents, GIP/GLP‑1 dual-target and triple-target agonists — clinical decision-making has become increasingly complex. Individualized regimens should be formulated by integrating patient phenotypes, drug mechanisms, weight-loss magnitude, metabolic improvement effects, and safety […]
Precision: The Inevitable Trend for Future Obesity Management
Professor Hong Tianpei of Peking University Third Hospital delivered a keynote report entitled Precision Therapy for Obesity: Opportunities and Challenges at the 2025 Peking University Diabetes Forum & Coastal Changqiao Metabolic Diseases Research Symposium. He shared insights on why precision represents the inevitable trend in future obesity management.Professor Hong Tianpei pointed out that obesity has […]