Diabetic microangiopathy is a major cause of disability and long‑term mortality in patients with type 1 diabetes mellitus (T1DM). As an essential micronutrient, magnesium participates in numerous enzymatic reactions and plays critical roles in maintaining cellular homeostasis, bone metabolism, neuromuscular function, and the regulation of inflammation and coagulation. However, clear evidence regarding the associations between […]
Tag: Type 1 diabetes
Association Between Oral-Gut Microbiota Dysbiosis and Chronic Vascular Complications in Long-Duration Type 1 Diabetes Patients
A cross-sectional study conducted by Professor Li Xia’s research team from the Second Xiangya Hospital of Central South University was published online in the journal Cardiovascular Diabetology. By integrating oral and gut microbiota analyses, this study reveals the association between microbiota dysbiosis and chronic vascular complications in patients with long-duration type 1 diabetes (T1D), providing […]
Thin Patients Do Not Necessarily Have Type 1 Diabetes
Being underweight does not necessarily indicate Type 1 diabetes; individuals may also develop Type 2 diabetes. Although Type 1 diabetes is typically associated with insufficient insulin secretion and patients are often lean, Type 2 diabetes can also occur in people with normal or low body weight.
Stem Cell-Reconstructed “Islets” Bring Hope to Type 1 Diabetes Patients
Recently, a Chinese research team published their latest online findings, marking the world’s first minimally invasive transplantation of regenerated islets (E-islets) derived from both autologous and allogeneic stem cells. This breakthrough successfully restored pancreatic islet function and enabled autonomous blood glucose regulation in patients with Type 1 Diabetes (T1D). It represents the first exploratory clinical […]
Unraveling the Immune Regulatory Mechanisms in Type 1 Diabetes Remission
Type 1 diabetes (T1D) is an autoimmune disease pathologically characterized by T‑cell‑mediated destruction of pancreatic islet β‑cells.Clinically, some patients with new‑onset T1D experience a transient remission phase, known as the “honeymoon period”: residual β‑cell function is partially restored, glycemic control is improved, and exogenous insulin requirements are reduced.However, the mechanisms underlying the initiation and maintenance […]
Residual Islet Function Still Exists in Patients with Long-Duration T1DM
During the 2025 Peking University Diabetes Forum and Coastal Long Bridge Symposium on Metabolic Diseases,Professor Gu Nan from the Department of Endocrinology, Peking University First Hospital, delivered a report on the current status and challenges of insulin therapy for type 1 diabetes mellitus (T1DM).Insulin replacement therapy is the core treatment for T1DM, but its clinical […]
Professor Zhou Zhiguang: Advances in Early Identification of Type 1 Diabetes
Type 1 diabetes (T1D) has an insidious onset and rapid progression. Many patients first present with severe complications such as diabetic ketoacidosis, imposing a heavy burden on individuals, families, and society. Therefore, strengthening early screening and early prevention of T1D is of great practical significance. At the recently held 27th Annual Conference of the Chinese […]
Is Diabetes Hereditary?
Diabetes does have a genetic tendency, but it is not a directly inherited disease. It is a metabolic disorder caused by the combined effects of genetic and environmental factors.Specifically:Type 1 diabetes has a relatively low heritability (about 3%–7%). Its genetic mechanism is closely related to the HLA gene (human leukocyte antigen), but it requires specific […]