New Clues Linking Magnesium Levels, Coagulation Function and Microvascular Complications in Pediatric and Adolescent Type 1 Diabetes

Diabetic microangiopathy is a major cause of disability and long-term mortality in patients with type 1 diabetes mellitus (T1DM). As an essential micronutrient in the human body, magnesium participates in a variety of enzymatic reactions and plays a vital role in maintaining intracellular homeostasis, bone metabolism, neuromuscular function, as well as regulating inflammation and coagulation. […]

Residual Islet Function Still Exists in Patients with Long-Duration T1DM

During the 2025 Peking University Diabetes Forum and Coastal Long Bridge Symposium on Metabolic Diseases,Professor Gu Nan from the Department of Endocrinology, Peking University First Hospital, delivered a report on the current status and challenges of insulin therapy for type 1 diabetes mellitus (T1DM).Insulin replacement therapy is the core treatment for T1DM, but its clinical […]

Clinical Staging and Three-Tier Prevention Strategies for T1DM

For a long time, insulin replacement therapy has been the cornerstone of treatment for type 1 diabetes mellitus (T1DM). However, clinical practice has long been challenged by issues such as the risk of hypoglycemia, weight gain, and aggravated insulin resistance. With in-depth exploration of disease mechanisms, the preservation of residual β‑cell function and adjuvant non‑insulin […]