Professor Andreas Liebl, Diabetes and Metabolism Center Bad Heilbrunn, Germany:New Management Approaches Address Patients’ Actual Barriers

Despite the growing body of evidence, many patients still face challenges such as poor treatment adherence and difficulty maintaining weight loss.Professor Andreas Liebl states:Indeed, I have encountered many patients who struggle greatly with weight loss even when we provide full support.In my opinion, one of the keys to success is to build an integrated multidisciplinary […]

Professor Andreas Liebl, Diabetes and Metabolism Center Bad Heilbrunn, Germany:Populations for Whom Weight Loss‑Centered Treatment Strategies Should Be Prioritized

Obesity has been recognized as one of the core therapeutic targets in type 2 diabetes mellitus (T2DM).Professor Andreas Liebl emphasizes that weight control itself is an independent therapeutic goal.However, given limited medical resources, it is essential to define priority populations.In his view, the following patient groups should receive prioritized intervention:First group: Early‑stage diabetes patients with […]

Professor Andreas Liebl (Diabetes and Metabolism Center Bad Heilbrunn, Germany): Reshaping the Future Landscape of T2DM and Obesity Management

Professor Andreas Liebl from the Diabetes and Metabolism Center Bad Heilbrunn, Germany, believes that the iteration and upgrading of innovative drugs will be most critical in the coming years. Drugs targeting GLP‑1, GIP, and glucagon receptors will be continuously optimized and diversified. As I noted earlier, such agents allow us to manage patients from a […]

Medications for Diabetic Kidney Disease: Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists

Mechanism of Action of GLP-1 Receptor AgonistsThey exert renal and cardiovascular benefits in many patients with diabetic kidney disease (DKD).Contraindications of GLP-1 Receptor AgonistsGLP-1 receptor agonists should be avoided in patients with a history of pancreatitis, a personal or family history of medullary thyroid carcinoma, or a personal or family history of multiple endocrine neoplasia.They […]

Medications for Diabetic Kidney Disease: Non-steroidal Mineralocorticoid Receptor Antagonist (MRA) – Finerenone

Renoprotective mechanism of non-steroidal mineralocorticoid receptor antagonist (MRA) – finerenoneReduces inflammation and fibrosis, lowers urinary protein excretion, and delays the progression of kidney disease.Contraindications and administration of finerenoneFinerenone should not be used in patients with serum potassium > 5 mmol/L or eGFR < 25 mL/(min·1.73m²). In patients initiated on a lower dose of finerenone, the […]

Medications for Diabetic Kidney Disease: Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors

Mechanism of Action of SGLT-2 InhibitorsIn patients with diabetes, sodium reabsorption is usually increased due to excessive glucose load in the renal tubules.SGLT-2 inhibitors reduce sodium reabsorption by blocking this cotransporter.The resulting natriuresis reduces intravascular volume and blood pressure, but also increases sodium delivery to the macula densa.This restores normal tubuloglomerular feedback and reduces intraglomerular […]

How Long Can You Live With Diabetic Kidney Failure?

Diabetic kidney failure often leads to cardiovascular and cerebrovascular complications, resulting in a relatively poor prognosis. However, with effective blood glucose control and complication prevention, patients can generally survive for about 20 to 30 years.Diabetic kidney failure usually progresses to uremia in approximately 10 years. With renal replacement therapy such as hemodialysis, survival can be […]