Professor Zhang Jie from the National Center for Geriatrics, Beijing Hospital, states that insulin degludec/insulin aspart has demonstrated consistent and significant HbA1c reduction and low hypoglycemia risk worldwide. The core behind this therapeutic consistency lies in its unique pharmacological design.Insulin degludec/insulin aspart is a soluble dual-component insulin formulation, composed of 70% ultra-long-acting insulin degludec and […]
Tag: diabetes treatment
Post-Marketing Multinational Real-World Studies of Insulin Degludec/Insulin Aspart: Confirming Its Efficacy and Safety
In the era of evidence-based medicine, randomized controlled trials (RCTs) provide robust evidence for new drug approval, while real-world evidence (RWE) helps reveal the actual performance of drugs in complex and diverse clinical settings. Since its global launch, insulin degludec/insulin aspart has not only demonstrated favorable efficacy and safety in registration trials but also continues […]
Treatment Strategies for Normocalcemic Primary Hyperparathyroidism (NPHPT)
According to Professor Jiaqiang Zhou from Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, the treatment strategies for normocalcemic primary hyperparathyroidism (NPHPT) vary among different patient groups and mainly include the following aspects:I. Monitoring and ManagementFor asymptomatic patients without target-organ damage, regular monitoring is recommended: Treatment plans should be adjusted promptly if disease […]
Treatment of Thyroid Diseases and Long‑Term Health Effects
A randomized controlled trial conducted by Ruijin Hospital, Shanghai Jiao Tong University School of Medicine showed that adding methotrexate 10 mg/week to standard thiamazole treatment significantly improved the remission rate off medication in patients with Graves’ disease (GD) at 15–18 months (55.6% vs. 38.9%) and accelerated the reduction of TSH receptor antibody (TRAb) levels, with […]
Medications for Type 2 Diabetes with Obesity
For patients with type 2 diabetes mellitus (T2DM) and obesity, pharmacotherapy should achieve both glycemic control and weight reduction. Based on extensive research and multiple medical guidelines, the following is a recommended medication strategy for such patients.I. Cornerstone Drug: Metformin (First-Line)As a first-line agent, metformin acts through unique mechanisms: It achieves dual benefits: glucose lowering […]
Timing Matters for Injections of Different Types of Insulin
Different types of insulin vary in onset and duration of action. For people with diabetes, it is essential to know which type they are using and follow the correct injection timing to achieve good glycemic control.Injection Timing of Insulin Types of Insulin
Tailoring the Choice of Weight-Loss Medications in Clinical Practice
Professor Xu Danyan, from the Department of Metabolic Cardiology at the Second Xiangya Hospital of Central South University, believes that if a healthy lifestyle is the foundation for fighting obesity, then weight-loss medications are the lever. With advances in medicine, the options for weight-loss medications have become more diverse, and they are currently categorized into […]
Intervention and Treatment of Postmenopausal Sarcopenic Obesity
Exercise Intervention: Multiple guidelines recommend resistance training as the core strategy for treating SO. Studies in postmenopausal women confirm that regular resistance training can significantly improve muscle strength and body composition, including increasing lean body mass and reducing fat percentage, in a safe and feasible manner.Nutritional Intervention: According to the ESPEN (European Society for Clinical […]
Clinical Consensus on Glycemic Management: Emphasizing Both Efficacy and Safety, with Consideration for Weight Control and Long-Term Benefits
Professor Chen Haibing from Shanghai Tenth People’s Hospital (Affiliated Tenth People’s Hospital of Tongji University) points out that diabetes is a highly heterogeneous disease driven by multiple factors in its onset and progression. Meanwhile, patients with diabetes often present with various comorbidities and complications, requiring comprehensive consideration in management. Pharmacotherapy should be administered when necessary […]
The Core of Precision Obesity Treatment is Patient-Centered Individualized Diagnosis and Therapy
Professor Hong Tianpei of Peking University Third Hospital holds that, with the continuous emergence of novel weight-loss medications — such as more potent GLP‑1 agents, GIP/GLP‑1 dual-target and triple-target agonists — clinical decision-making has become increasingly complex. Individualized regimens should be formulated by integrating patient phenotypes, drug mechanisms, weight-loss magnitude, metabolic improvement effects, and safety […]