Long-term Sleep Deprivation May Increase the Risk of Diabetes

Long-term sleep deprivation may increase the risk of diabetes, which is closely linked to disruptions in the body’s hormonal balance and metabolic function. Below is a detailed explanation of this connection and its related effects.Insomnia or staying up late triggers increased secretion of glucose-raising hormones such as adrenaline and cortisol. Excessive secretion of these hormones […]

Risk Factors for Various Thyroid Diseases

According to a study by Adams et al., when administered the same dose of thyroid hormone per unit body weight, elderly women are more susceptible to iatrogenic thyrotoxicosis than men, which may be related to gender differences in body composition. Calculating the drug dosage based on ideal body weight or lean body mass instead of […]

Mechanism of Osmotic Diuresis

Osmotic diuresis refers to a physiological or pathological process in which increased solute concentration in the tubular fluid reduces water reabsorption by the renal tubules, resulting in abnormally increased urine output.I. Hyperglycemic Osmotic DiuresisWhen blood glucose rises significantly (e.g., >10 mmol/L in diabetic patients), glucose filtered by the glomeruli cannot be fully reabsorbed by the […]

Differences Between Osmotic Diuresis and Water Diuresis

Osmotic diuresis refers to a diuretic phenomenon in which an increased solute concentration in the renal tubules and collecting ducts raises osmotic pressure, impairs water reabsorption, and results in increased urine output. It disturbs the metabolic balance of body fluids and electrolytes.Polyuria in diabetic patients is caused by osmotic diuresis. Due to impaired islet function, […]

iCARDIO 2025 Guidelines Landmark Release: Redefining Obesity and Its Significance

Obesity has long been mistakenly regarded as merely a “physical appearance issue” or a “lifestyle choice.” In October 2025, the iCARDIO Alliance Global Implementation Guidelines for Obesity Management 2025 (iCARDIO 2025 Guidelines for short) was officially released. It clearly defines obesity as a chronic, relapsing, multifactorial metabolic disease and places it at the core of […]

Pathogenesis of Postmenopausal Sarcopenic Obesity

During the 27th Annual Conference of the Chinese Society of Diabetes (CDS 2025), a premier event in the diabetes field, top experts and scholars from across the country gathered to conduct in-depth exchanges on cutting-edge topics in endocrinology and metabolism, yielding fruitful academic outcomes. At the conference, Professor Shen Jie from the Eighth Affiliated Hospital […]

Professor Chen Yanming: Metabolic Damage Dominates Early-Stage Diabetic Retinopathy

Diabetic retinopathy (DR) is one of the leading causes of blindness among the working-age population worldwide. Traditionally regarded as a typical microvascular disease, a growing body of research clearly demonstrates that retinal metabolic damage is not a passive accompaniment but a causal origin driving neurovascular destruction.At the 27th Annual Conference of the Chinese Society of […]

MASLD Increases All-Cause Mortality Risk in Type 2 Diabetes

Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly becoming one of the most prevalent chronic liver diseases worldwide. Although the disease directly impairs liver function, causing abnormal fat accumulation and hepatocellular injury, its most life-threatening threat often does not originate from liver lesions themselves. In fact, MASLD more commonly significantly elevates patients’ all-cause mortality risk […]

Three Types of People at High Risk of Type 2 Diabetes

Most patients with type 2 diabetes do not rely on insulin at the initial onset, and can use oral hypoglycemic drugs to control blood glucose. It is also known as non-insulin-dependent diabetes.The so-called “type 2 diabetes” develops through a long pathological process under the action of various pathogenic factors.Who are at high risk of type […]

If One Spouse Has Diabetes, the Other Should Increase Monitoring

Living together as a couple means sharing obligations and responsibilities, but it may also mean sharing each other’s risk of diabetes. A study from McGill University in Canada found that having a spouse with diabetes increases the risk of the partner developing the disease.Recently published in the open-access journal BMC Medicine, this finding carries important […]