Acanthosis Nigricans May Lead to Diabetes

Acanthosis nigricans is a skin disease, while diabetes is a metabolic disease. They are not the same type of condition.However, patients with acanthosis nigricans tend to develop hyperinsulinemia and insulin resistance in the body, which over time can induce diabetes. Many patients with acanthosis nigricans also develop diabetic complications. The detailed analysis is as follows:Acanthosis […]

What to Do About Hair Loss in Diabetic Patients?

Hair loss in people with diabetes can be improved by controlling blood glucose, adjusting diet, supplementing nutrition, reducing stress, and using medications.Hair loss may be related to poor blood glucose control, malnutrition, high mental stress, hormonal imbalance, side effects of drugs, and other factors. If there is heavy hair loss or alopecia areata, seek combined […]

The Relationship Between Hyperlipidemia and Diabetes

I. Pancreatic β-Cells Under Lipotoxic AttackHyperlipidemia acts as a hidden silent killer, especially the surge in free fatty acids and triglycerides, which inflicts lipotoxicity on pancreatic β-cells.Excess lipid deposition in β-cells opens a Pandora’s box, triggering endoplasmic reticulum stress and mitochondrial dysfunction, severely inhibiting insulin synthesis and secretion.Under long-term lipotoxic assault, β-cells may undergo apoptosis, […]

The Genetic Mechanism of the “Neuro-Adipose Regulatory Axis” Underlying Obesity

On January 15, 2026, the research team led by Professor Weng Jianping (President of Anhui Medical University, Chair Professor at University of Science and Technology of China) and Researcher Zheng Xueying published a study in Metabolism entitled “Integrative Functional Genomics and Fine-Mapping Identify Regulatory Mechanisms of Multivariate Obesity GWAS and Its Cardiometabolic Implications”.By constructing an […]

Core Diagnostic Criteria and Pathogenesis of Normocalcemic Primary Hyperparathyroidism (NPHPT)

Normocalcemic primary hyperparathyroidism (NPHPT), a special subtype of primary hyperparathyroidism (PHPT), is easily overlooked in clinical practice due to normal serum calcium levels and insidious early symptoms. With the popularization of serum calcium screening and advances in imaging technology, the detection rate of NPHPT has been increasing year by year.At the Chinese Endocrinologist Association Annual […]

Long-term Sleep Deprivation May Increase the Risk of Diabetes

Long-term sleep deprivation may increase the risk of diabetes, which is closely linked to disruptions in the body’s hormonal balance and metabolic function. Below is a detailed explanation of this connection and its related effects.Insomnia or staying up late triggers increased secretion of glucose-raising hormones such as adrenaline and cortisol. Excessive secretion of these hormones […]

Risk Factors for Various Thyroid Diseases

According to a study by Adams et al., when administered the same dose of thyroid hormone per unit body weight, elderly women are more susceptible to iatrogenic thyrotoxicosis than men, which may be related to gender differences in body composition. Calculating the drug dosage based on ideal body weight or lean body mass instead of […]

Mechanism of Osmotic Diuresis

Osmotic diuresis refers to a physiological or pathological process in which increased solute concentration in the tubular fluid reduces water reabsorption by the renal tubules, resulting in abnormally increased urine output.I. Hyperglycemic Osmotic DiuresisWhen blood glucose rises significantly (e.g., >10 mmol/L in diabetic patients), glucose filtered by the glomeruli cannot be fully reabsorbed by the […]