Types and Treatment of Monogenic Diabetes

MODY (Maturity-Onset Diabetes of the Young):MODY1 (HNF4A gene mutation): Blood glucose gradually increases with age, and patients are sensitive to sulfonylureas.MODY2 (GCK gene mutation): Mildly elevated blood glucose, usually does not require medication.MODY3 (HNF1A gene mutation): Onset in adolescence; low-dose sulfonylureas are more effective than insulin.Neonatal Diabetes Mellitus:Onset occurs within 6 months of age. Approximately […]

What is Monogenic Diabetes?

Monogenic diabetes is a special type of diabetes caused by a mutation in a single gene, accounting for approximately 1%–5% of all diabetes cases. It is often misdiagnosed as type 1 or type 2 diabetes due to its atypical symptoms. Diagnosis relies on genetic testing. Some types can be precisely treated with specific medications (such […]