Diabetic peripheral circulation disorder is a complication in diabetic patients caused by long-term hyperglycemia, which leads to microangiopathy and peripheral nerve injury, resulting in insufficient blood supply to the extremities (such as hands and feet).It is characterized by numbness, pain, coldness and other symptoms, and may lead to ulceration or necrosis in severe cases.
I. Pathogenesis
Microvascular injuryLong-term hyperglycemia damages vascular endothelial cells, resulting in vascular stenosis and reduced blood flow, especially affecting the peripheral extremities.
NeuropathyHyperglycemia impairs nerve cells and conduction function, reducing the patient’s perception of temperature and pain, which further increases the risk of injury.II. Typical Symptoms
Numbness, stabbing pain or burning sensation in the hands and feet, which worsens at night;
Decreased skin temperature, pale or purplish skin discoloration;
Slow wound healing, with minor injuries possibly developing into chronic ulcers;
In severe cases, rest pain (pain at rest) or tissue necrosis may occur.