LDL-Cholesterol Targets for People with Diabetes

Patients with diabetes combined with dyslipidemia have a significantly increased risk of cardiovascular disease.Among these, poor control of low‑density lipoprotein cholesterol (LDL‑C) is recognized as the primary risk factor.
For people with diabetes, individualized LDL‑C targets should be set based onwhether they have atherosclerotic cardiovascular disease (ASCVD) and their age.
Patients without atherosclerotic cardiovascular disease

Under 40 years old: LDL‑C ＜ 2.6 mmol/L
40 years old and above: LDL‑C ＜ 1.8 mmol/L

Patients with atherosclerotic cardiovascular disease

Very high risk: LDL‑C ＜ 1.8 mmol/L,
with a reduction of ≥50% from baseline LDL‑C.
Extremely high risk: LDL‑C ＜ 1.4 mmol/L,
with a reduction of ≥50% from baseline LDL‑C.

Patients over 80 years old
For those with short life expectancy, poor general health, or severe complications,appropriately relaxed targets are recommended.